Pregalin 150mg Capsules

What is Pregalin 150mg?

Pregalin 150mg is an anticonvulsant, anxiolytic, and analgesic. Pregalin 150mg is a drug used to treat Fibromyalgia, epilepsy, restless leg syndrome, neuropathic pain, opioid withdrawal, and generalized anxiety disorder (GAD).

In the United States in 2004, this medicine was first approved and was developed to provide an alternative to Gabapentin. In 2019, this drug was rated the 81st most commonly prescribed medication in the United States. Pregalin 150mg in the United Kingdom is a Class C controlled substance.

Pregalin 150mg Capsule is a medicine used relieve pain associated with nerve damage (neuropathic pain) due to diabetes, shingles (herpes zoster infection), spinal cord injury, or other conditions. Furthermore, its main function is to reduce pain before surgery. Moreover, it also causes increased sedation and visual disturbances. Pregalin 150 mg is taken using oral administration via the mouth.

How does Pregalin 150mg Capsule Work?

Pregalin 150mg works by inhibiting certain calcium channels. 

Specifically, it is a ligand of the auxiliary α2δ subunit site of a few voltage-dependent calcium channels VDCCs. Thus, it inhibits α2δ subunit-containing VDCCs. In terms of drug-binding α2δ subunits, it is to α2δ-1 and α2δ-2 that Pregalin 150 mg shows an affinity. This drug is also selective while binding to the α2δ VDCC subunit. In addition, Pregalin 150 mg does not bind to the GABA receptors. Furthermore, Pregabalin 150 mg is known to produce a dose-dependent increase in the brain expression of L-glutamic acid decarboxylase (GAD), an enzyme known to synthesize GABA. Currently, there is no evidence that this drug works by a mechanism other than that which involves the inhibition of α2δ-containing VDCCs.

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What is The Chemical Composition of Pregalin 150mg?

The chemical structures of Pregalin 150 mg comprise two gabapentinoids which include Phenibut and Gabapentin.  

Do You Know The Drugs That Interact with Pregalin 150mg, and How Long does Its Effect Last?

 A fact to be noted is that using Pregabalin 150 mg with other drugs can slow your breathing and trigger dangerous side effects or death. Therefore, you must ask your doctor before using Pregabalin 150 mg and other medications like opioid drugs, allergy medicine, muscle relaxer, or medicine for anxiety or seizures. 

Some of the drugs that interact with this medicine include the following: 

• ACE inhibitors such as ramipril, or trandolapril, benazepril, captopril, enalapril, fosinopril, and lisinopril, moexipril, perindopril, and quinapril.
• A few oral diabetic medications like pioglitazone, rosiglitazone, etc.

The duration of action of this drug is not known.

What are The Medical Uses of Pregalin 150mg?

The analgesic and anticonvulsant drug Pregalin 150mg are used in the treatment of the following medical conditions:  

• Diabetic Neuropathy
• Nerve pain or Fibromyalgia
• Herpes Zoster
• Spinal Cord
• Partial onset seizures  

 Do You Know about The Dosing Schedule of Pregalin 150mg Capsule?

It is advisable to take Pregalin 150mg as your doctor prescribes. Moreover, it would help if you kept in mind that your physician may change your dose. There are a few tips you need to know while taking this drug. They are as below:

• Take Pregalin 150 mg simultaneously, with or without food, every day.
• Do not chew, break, or crush the extended-release Pregalin 150 mg tablets; instead, swallow them whole.
• Even if you feel flawless, avoid abruptly ceasing to use Pregalin 150 mg.
• Please store away from moisture, heat, and light at room temperature. Keep it away from children.

What Happens If You Miss A Dose of Pregalin 150mg?

If you miss a dose of Pregalin 150 mg, please take it as soon as you remember. Avoid taking a double dose of the medication.

Are you aware of what you need to do if you overdose on Pregalin 150mg?

If you overdose on Pregalin 150 mg, you should seek medical attention immediately.

Do You Know The Side Effects of Taking Pregalin 150 mg Capsules?

The use of Pregalin 150mg can exert the following side effects. They are as below:

• Difficult breathing
• Swelling on the lips, tongue, throat, or face is possible.
• Formation of hives or blisters on your skin
• Depression, anxiety, or panic attacks
• Insomnia
• Feelings of hostility, irritability, aggression, and restlessness
• Mental hyperactivity
• Suicidal thoughts

There are several side effects that you possibly may experience on taking Pregalin 150 mg. They are:

• Vision issues 
• Skin sores formation 

• Muscle Pain 
• Swelling in your hands or feet, and rapid weight gain
• Weak or shallow breathing 
• Confusion, extreme drowsiness, or weakness 
• Blue-colored lips, fingers, or toes  

Do You Know The Precautions You must Consider While Taking Pregalin 150mg Capsule?

 Before taking Pregalin 150mg, if you have the following medical conditions mentioned below, you must take precautions by informing your doctor. They are: 

• A severe allergic reaction; low platelet counts or a bleeding condition; addiction to drugs or alcohol

• Diabetes (unless pregabalin is being used to treat diabetic neuropathy)

• Kidney illness (or if you are on dialysis)

• Heart conditions (especially congestive heart failure)

• An emotional disturbance, depression, or suicidal ideas;

• Medical conditions of the lungs, such as chronic obstructive pulmonary disease (COPD) 

Are You Aware of The Brand Names of Pregalin 150mg?

 Lyrica and Lyrica CR are some of the brand names of Pregalin 150 mg. 

How do You Take Pregalin 150mg Capsule?

Measure the liquid Pregalin 150mg medication precisely. Use a medicine dose-measuring tool or the dosage syringe provided (not a kitchen spoon). It is important to call your doctor if symptoms do not improve or get worse despite taking Prebagid. Above all, please follow your doctor’s advice of reducing the dose for one week before you completely stop consuming it.  

If you are facing a medical emergency, please carry medical identification to help everyone know that you are taking seizure medication.

Frequently Asked Questions.  

Q. How Efficient is Pregalin 150mg for Pain?

When used, Pregalin 150mg helps in reducing nerve pain very significantly. In case of pain caused by diabetes, too, this medication effectively helps provide relief.  

Q. For What Medical Conditions are Pregabaid 150mg Used?

It is mainly in the treatment of epilepsy and anxiety that Pregalin 150mg is used. In addition, if this drug is taken, you suffer from severe nerve pain. Furthermore, nerve pain can be triggered by diabetes, shingles, or even an injury.  

Q. Can You Use Pregabaid 150mg As A Sleep Medication?

Generally speaking, Pregalin 150 mg is used as an anticonvulsant drug. However, it is found that this drug can also improve sleep quality significantly in patients who suffer from Fibromyalgia, neuralgia, or epilepsy. 

Q. How Long can You Take Pregabaid 150 mg Capsule?

You can use Pregalin 150 mg for as long as you need it to provide relief from pain, epileptic attacks, or bouts of anxiousness. Moreover, you must review by visiting a doctor or pharmacist every six to twelve months. 

You must also remember that if you have had Pregalin 150mg for a long time, it may not work well or may not be needed.  

Q. Does The Use of Pregalin 150mg Cause Renal Damage?

The use of Pregalin 150mg can cause serious kidney damage. If you find your kidneys not functioning properly after taking the drug, you must seek medical attention. Symptoms include a decrease in urine produced, difficulty in urinating, swelling of legs and ankles, or increased urination urge at night. However, before these signs worsen, you should contact your doctor as soon as possible.