Nucynta 100 mg was in November 2008 that the FDA of the United States of America approved Nucynta 100mg officially for medical use. Meanwhile, Australia’s TGA (Therapeutic Goods Administration) approved the drug in December 2010. The Central Drug Standard Control Organisation (CDSCO) in India permitted the use of immediate-release preparation and extended-release for moderate to severe acute pain in April 2011 and December 2013, respectively.
What is Nucynta 100 mg?
Nucynta 100 mg is a central nervous system opioid analgesic contains Tapentadol prescribed for moderate to sever acute pain. It works to alter the way the body responds to pain. Nucynta 100 mg is administered orally, with its duration of action lasting four to six hours. This drug also possesses similar potency exuded by tramadol and morphine.
Nucynta 100 mg (Tapentadol) is used in the form of immediate release (IR) & extended-release (ER) for the treatment of moderate to sever pain. Immediate release Nucynta (IR) 100 mg tablet helps to treat pain that can relieve immediately like headech. Extended release Nucynta (ER) 100mg tablet used for diabetes patients who suffer from severe neuropathic pain (pain from nerve damage).
On first consuming Nucynta 100 mg, it takes about thirty-two minutes for the ‘Analgesia’ effect to begin working. In terms of its mechanism of action, this medicine acts by initially activating the mu-opioid receptor, then inhibiting the reuptake of norepinephrine. However, it only weakens the reuptake of serotonin, which is very unlike how tramadol works. It is a fact that the analgesic efficacy of Nucynta 100mg is comparable to that of oxycodone. Generally speaking, this medicine is considered to be a moderately strong opioid.
How does Nucynta 100 mg Tablet Work?
Nucynta 100 mg is essentially an analgesic, an opioid (narcotic) pain medicine used in the treatment of moderate to sever acute pain. It acts as a dual agonist on the μ-opioid receptor and the norepinephrine reuptake inhibitor. Therefore, its opioid analgesic effect is exerted when the drug on consumption stimulates the mu-opioid receptor and inhibits the reuptake of norepinephrine. Moreover, the potency of Nucynta 100mg proves to be at least eighteen times less potent than morphine. The commercial preparations of this medicine comprise only the least powerful isomer regarding opioid activity, i.e. (R, R) stereoisomer.
What are The Uses of Nucynta 100 mg Tablets?
Nucynta 100 mg is a drug you can use to treat moderate-to-severe pain that arises due to the following medical conditions:
Musculoskeletal Pain:
In this type of disease, you experience moderate-to-severe pain due to injuries in the musculoskeletal region of your body, including ligaments, muscles, tendons, joints etc. Thus, consuming Nucynta 100 mg can eliminate musculoskeletal symptoms such as stiffness, aching, fatigue, muscle cramps, and sleep disturbances.
Diabetic Neuropathy:
It is a medical condition with a direct association between peripheral nerve damage that includes motor and sensory neurons and diabetes mellitus. Therefore, by using Nucynta 100 mg, you can eliminate some of its symptoms, such as burning or tingling, muscle weakness, cramps, sharp pain, and numbness.
Moreover, you must note that Nucynta 100mg is not recommended for use in pregnant women, especially just before labor and delivery.
Drug Interactions with Nucynta 100 mg:
You consume many drugs, along with Nucynta 100 mg, that may hurt your health. If you use the following drugs mentioned below, you must inform your doctor.
- Wide range of other opioid medicines
- Antidepressants and stimulants which affect serotonin
- Muscle relaxants or sleep medication that exert drowsiness
- Blood pressure, asthma, allergies, motion sickness etc. drugs
- Sedatives belonging to the benzodiazepine family
More importantly, you must also understand that there are about 372 drugs that can interact with Nucynta 100mg and have an impact on your body.
Dosing Schedule of Nucynta 100 mg:
The dosing plan for the Nucynta 100 mg depends on the pain you experience.
Therefore, the plan set for using this medication is as follows:
Adult Dose for Acute Pain:
For immediate release, the initial dose you need to take orally is 50 to 100 mg on an as-needed basis every four to six hours. Furthermore, you can take the second dose an hour after completing the first dose. You can continue taking the rest of the dosage every four to six hours. More importantly, you need to adjust the dose to your ability to tolerate the analgesic effect.
Adult Dose for Chronic Pain:
If you suffer from chronic musculoskeletal pain, you need to individualize and create a Nucynta 100mg dosage plan.
It means certain factors, such as pain severity, responses to pain therapy, addiction/abuse/misuse of a substance, and prior experience with the analgesic treatment, you need to consider.
Missed-Dose Guidelines:
Since Nucynta 100mg is an opioid analgesic used to provide relief from pain, you do not need to take it daily but on an as-needed basis. Thus, the chance of skipping a dose is minimum. However, if you miss a dose, you must ensure that you do not compensate for it if the time for the fresh dose is just around the corner. Besides, you must also, for twenty hours, try not to consume the prescribed dosage of this medication.
Overdosage Gudelines:
Firstly, as soon as you overdose on Nucynta 100mg and observe symptoms such as slow or no breathing, pinpoint pupils and even severe drowsiness, you need to call your doctor or any other healthcare specialist immediately. Secondly, your physician may recommend that you use naloxone. More importantly, you need to ensure that you have someone in the family who knows how to use this drug and all about the storage information of Nucynta 100mg.
What are The Side-Effects of Nucynta 100 mg Tablets?
There are several side effects that you may experience on consuming Nucynta 100 mg.
Hence, if you observe the following symptoms given below, then it is essential to get medical attention immediately.
They are as follows:
- Pain in the chest
- Breathing difficulty
- Rapid heartbeats
- Swelling of face, tongue, throat, lips
- Constipation
- Nausea
- Vomiting
- Headache
- Dizziness or drowsiness
You must be aware that Nucynta 100mg is an opioid or narcotic medication; it can also cause a few adverse effects, such as slow or no breathing. Also, there are a few others that you need to know about, and they are as follows:
- Seizure
- Decrease in cortisol levels resulting in symptoms like nausea, vomiting, appetite loss
- A lightheaded feeling
- Feeling hot
- Serotonin syndrome
- Shallow and noisy breathing
- Speech and balance issues
Furthermore, Nucynta 100mg is more likely to cause serious breathing problems in older adults or those individuals whose immunity is compromised and therefore suffer from medical conditions such as wasting syndrome.
While Taking Nucynta 100 mg, what must You Avoid?
Before consumption of Nucynta 100 mg, you must stop drinking alcohol. Doing so can trigger lethal side effects and may even lead to death. Furthermore, you must avoid driving or performing any other such hazardous activity till the time you understand the effect that Nucynta 100mg has on your body.
Precautions You Need to Watch for before Taking Nucynta 100 mg:
If you have ever used an MAO inhibitor fourteen days before the intended use of Nucynta 100 mg, then you must not use this drug. A few MAO inhibitors include linezolid and methylene blue injection. In addition, you must also not use Nucynta 100mg if you have serious breathing problems or bowel obstruction issues such as paralytic ileus.
The Brand Names of Nucynta 100 mg:
Some of the brand names of Nucynta 100mg include Yantil, Palexia, Tapal, and Aspadol.
Frequently Asked Questions:
Q. How do You Store Nucynta 100 mg?
In terms of storage, you must keep Nucynta 100mg away from the environment in a cool and dry place.
Therefore, you can store it in places such as a kitchen cabinet or dresser drawer far away from the stove or sink and be exposed to hot appliances.
Q. What is the effect of Nucynta 100mg on your brain?
Nucynta 100mg is a narcotic analgesic that directly acts upon opioid receptors in the central nervous system. Besides, this drug consumption helps in reducing the feeling of pain by disturbing the nerve signals that pass between the brain and the other parts of the body.
Q. Is there a risk of acquiring addiction while taking Nucynta 100mg ?
Like other allopathic medications, taking Nucynta 100mg for a longer period may become a habit or a form of addiction.
Moreover, people suffering from chronic moderate-to-severe pain must not let the fear of becoming dependent prevent them from consuming Nucynta 100mg.
Q. When do you use Nucynta 100mg ?
You can use Nucynta 100mg as your doctor prescribes if you suffer moderate-to-severe pain. However, if you suffer from medical conditions such as breathing problems, stomach or bowel obstructions, severe asthma, etc., you must avoid taking this drug. In addition, if you have been on an MAO inhibitor for fourteen days before using Nucynta 100mg, you need to stop taking it immediately.
Q. Can you feel euphoric on taking Nucynta 100mg?
Nucynta 100mg is a drug that exerts very distinctive μ-opioid receptor agonistic effects. Therefore, the mood alteration that this medication can produce is far less than other potent narcotics.
Q. Is 100 mg of Nucynta an appropriate dose?
It is in the dosage range of 50 to 100 mg within four to six hours as needed that a doctor will recommend you take Nucynta. More importantly, before beginning your dose as per the plan prescribed by a physician, you need to taper every three days.
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