What is Naprosyn ?
Naprosyn (Naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) that contains Naproxen. Naprosyn (Naproxen) is used to relieve inflammatory conditions associated with headache, muscle pain, tendonitis, tooth pain, menstrual cramps etc. & inflammatory diseases such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout & juvenile arthritis. It is a non-steroidal anti-inflammatory drug that is taken via the oral route. Naprosyn tablet is a pain relieving medicine work to reduce pain, swelling, and joint stiffness caused by arthritis, bursitis and gout attacks. In terms of formulations, this medication is available in immediate and delayed release. People suffering from renal issues must avoid using Naprosyn.
Naprosyn functions as a nonselective COX inhibitor. It serves by exerting its anti-inflammatory action by eliminating the production of inflammatory mediators known as ‘Prostaglandins.’ Naprosyn undergoes metabolism in the liver to be produced in the form of inactive metabolites.
This drug was, for the first time, officially approved for medical use in the United States in 1976. It was in 2019 that Naprosyn became the 61st most commonly prescribed medication in the United States of America.
Ho does Naprosyn Tablet Work ?
Naprosyn works by extensively triggering the inhibition of both COX-1 and COX-2 enzymes. It triggers the inhibition of prostaglandin synthesis. It results in prostaglandins acting like signaling molecules in the body leading to the induction of inflammation. In other words, it is by inhibiting COX-1/2 that Naprosyn produces its anti-inflammatory effect.
Naproxen works by inhibiting the activity of an enzyme called cyclooxygenase (COX), which is responsible for producing chemicals called prostaglandins. Prostaglandins are involved in the body’s inflammatory response and are responsible for producing pain, swelling, and fever.
Naproxen blocks the COX enzyme, which in turn reduces the production of prostaglandins. This reduces inflammation, swelling, and pain. Naproxen is classified as a non-selective COX inhibitor, meaning it blocks both COX-1 and COX-2 enzymes. COX-1 is involved in the production of protective prostaglandins in the stomach and intestines, while COX-2 is involved in the production of inflammatory prostaglandins in injured tissues.
By blocking both COX-1 and COX-2 enzymes, naproxen can cause side effects such as stomach upset, heartburn, and gastrointestinal bleeding. However, it is also effective in treating a wide range of conditions such as arthritis, menstrual cramps, headaches, and fever.
What are The Uses of Naprosyn Tablets?
Naprosyn (Naproxen) is a non-steroidal anti-inflammatory drug used to treat pain & inflammation due to osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout & juvenile arthritis. It acts by lowering the presence of hormones that are responsible for pain and inflammation in the body.
Its clinical application mainly includes the reduction of inflammation or pain brought on by rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.
What are The Dosage Guidelines of Naprosyn Tablets?
You must follow the manufacturer’s instructions for Naprosyn strictly, or use it as your doctor has advised. Never take this medication in excess or for longer than advised. The lowest dose that will effectively treat your illness should be used.
Before you measure a dose:
- Give the oral suspension (liquid) a good shake.
- Use the accompanying dosing syringe, a dose-measuring spoon, or a medicine cup to measure liquid medications.
- Ask your pharmacist for a dose-measuring tool if you don’t already have one.
Your dosage requirements may alter if you switch naproxen brands, strengths, or dosage formats. If you have any concerns about the brand of naproxen, you need to ask your pharmacist.
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Chemical Structure of Naprosyn ?
It is to the 2-aryl propionic acid (profen) branch within the NSAID family that Naprosyn belongs. It is a white crystalline organic compound that is essentially odorless in taste, lipid-soluble, and practically insoluble in water.
The Drugs That Interact with Naprosyn, and How Long does It Take to Effect?
If you use antidepressant-like citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone, you must see your doctor before taking Naprosyn. Since taking any of these medications combined with an NSAID may make you more prone to bleeding or bruises.
If you also take any of the following medications mentioned below, you need to see your doctor or pharmacist determine whether it is safe for you to use Naprosyn: They are
- Diabetes medication
- A water pill or diuretic
- Blood Pressure or Heart medication
This medication takes about two to four hours post-administration to take effect on the body to relieve pain.
What must You Do If You Miss a Naprosyn Dose?
It is more likely that you may not be on a dosage plan because Naprosyn is occasionally used as needed. In case of a missing dose, then you can take it as soon as you remember. Skip the missed dose if the scheduled dose is just around the corner. Do not take more medication if you want to make up for a missed dose.
Overdosage Guidelines on Naprosyn
Taking a Naprosyn dose can lead to overdosing at times. In such a situation, you must seek medical attention immediately or call a helpline.
What are The Side Effects of Naprosyn Tablets?
After taking a Naprosyn, you may experience symptoms such as runny or stuffy nose, wheezing or difficulty breathing, hives, swelling in your face or throat or a severe skin reaction; seek emergency medical attention right once fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling.
If you experience a severe medication reaction impacting numerous body parts, stop taking this medicine and get medical help. Skin rash, fever, swollen glands, muscle aches, extreme weakness, unusual bruising and yellowing of the skin or eyes are a few symptoms that can occur.
In case of the following symptoms, including a heart attack or stroke: chest discomfort, abrupt numbness or weakness on one side of the body, slurred speech, or feeling out of breath, you need to get emergency medical attention as soon as possible.
A few other common side-effects include the following:
- Ringing in ears
- Bruising, itching, and rash
- Headache, drowsiness, or dizziness
- Indigestion, heartburn, and stomach pain
If you experience any of the adverse effects from taking this medication below, then you need to call your doctor immediately. They include:
- Liver problems
- Reduction in red blood cell count or Anemia
- Signs of stomach bleeding
- Renal problems
- Severe skin reaction
- Shortness of Breath
- Rapid weight gain
The Drugs That We Need to Avoid While Taking Naprosyn Tablet?
It would help if you stayed clear of alcohol since consuming it may increase the risk of stomach bleeding. It would help if you did not take Aspirin and other NSAIDs unless your doctor instructs you to do so.
Before taking any additional medicines for pain, arthritis, fever, or swelling medicine, consult your doctor. Many over-the-counter medications include aspirin, salicylates, or other drugs comparable to naproxen (such as ibuprofen or ketoprofen).
It is necessary that before taking an antacid, you consult your doctor and only take the brand they advise. Some antacids can hinder your body’s ability to absorb naproxen, which you must keep in mind.
Precautions Guidelines for Naprosyn Tablets?
There is a possibility that you may have previously experienced an adverse response to aspirin or another NSAID; in such case, you should avoid using Naprosyn.
If you use the drug for an extended period, at large dosages, despite having heart problems, or take it frequently, your chance of fatal heart attack or stroke may increase. While using this medication, people with or without risk factors for heart disease may get a stroke or heart attack.
Naprosyn before or after cardiac bypass surgery is not advisable (coronary artery bypass graft, or CABG).
If you have ever experienced an asthma attack or a severe allergic reaction after taking aspirin or an NSAID, you should not use this drug. You should avoid using it if you are sensitive to naproxen.
In addition, before you provide this drug to a child under the age of 12, consult a doctor.
Above all, before you consume these tablets, ensure that you consult a physician or pharmacist to determine whether it is safe for you to use this medication.
How do You Take Naprosyn Tablet?
Depending on your dosage requirements, you may use Naprosyn. If you have any concerns about the brand of naproxen you are taking, then you need to ask your pharmacist.
If your kid is on this medication, let your doctor know if they see any weight changes. Children’s Naprosyn dosages are to be decided by weight; thus, any adjustments you make may impact you.
Long-term Naprosyn users may require routine medical examinations.
With some medical tests, this medication may produce unexpected findings. Inform any medical professional that you are taking this drug.
You must store away this medication from moisture, heat, and light at room temperature. When not in use, keep the bottle tightly closed and away from children.
Frequently Asked Questions.
Q. Is Naprosyn a painkiller?
It relieves pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and pediatric arthritis. It also helps ease headaches, toothache, menstrual cramps, and muscle and joint pain.
Q. When do you need to take Naprosyn ?
To prevent gastrointestinal irritation:
- Take Naprosyn tablet with food.
- Avoid crushing, chewing, or breaking the tablet.
- Never exceed the recommended dose.
- Take this medication every day at around the same time.
Q. Does the use of Naprosyn lead to increased blood pressure?
If taken especially at higher doses, NSAIDs can increase your risk of heart attack or stroke. This medication commonly causes blood pressure and includes Advil, Motrin, and Ibuprofen (Aleve, Naprosyn).
Q. How safe is Naprosyn for consumption?
The use of NSAIDs, such as Naprosyn, may result in ulcer, bleeding, or holes in the stomach, intestine, or esophagus. These issues can arise at any point during therapy without prior symptoms and can potentially be fatal.
Q. While on Naprosyn, do you feel drowsy?
Oral naproxen tablets on prescription may make you sleepy. Therefore, driving, operating machinery, and engaging in other tasks that call for alertness should all be avoided until you can perform them regularly. Other adverse effects of this medication are also possible, which you must keep in mind.