Ciprofloxacin 500 mg Hydrochloride Tablets

What is Ciprofloxacin 500 mg ?

Ciprofloxacin 500 mg is a fluroquinoline antibiotic medicine used in the treatment of several bacterial infections of respiratory tract, skin, joints, bones, infectious diarrhoea. It works to prevent the growth of bacterial infecions. It possesses a broad spectrum activity which works to very effectively kill bacteria. Ciprofloxacin 500 mg acts by inhibiting the enzyme cytochrome P450 1 A2 which generally metabolizes drugs. On oral administration, this medicine is only about 70%.

In 1980 Ciprofloxacin 500 mg first got its patent and was introduced into the market in 1987. This drug is on the World Health Organization‘s List of Essential Medicines.In 2019, this medication was the 113th most regularly prescribed drug in the United States of America. More than five million prescriptions of Ciprofloxacin 500 mg were recorded during the year.

How does Ciprofloxacin 500 mg Hydrochloride Tablet Work?

Ciprofloxacin 500 mg is active against both gram-positive and gram-negative bacteria. Ciprofloxacin 500mg is a broad-spectrum antibiotic belongs to the Fluoroquinolone family. It is prescribed to treat certain bacterial infections associated with joint, bone, skin, respiratory tract infections, and infectious diarrhoea. This drug prevents enzymes II topoisomerase (DNA gyrase) and topoisomerase IV from separating bacterial DNA by exerting inhibition on cell division. Bacterial DNA fragmentation will happen due to the inhibition of enzymes. Thus, when it absorbs in the body after consumption, it exerts its action by inhibiting the function of the bacterial enzyme DNA gyrase. Which in simple words means that by applying inhibition on cell division, it prevents bacterial cells from dividing and repairing to kill them. 

Chemical Structure of Ciprofloxacin 500 mg Tablet

Ciprofloxacin 500 mg is a Fluoroquinolone antibiotic with the following chemical structure 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid. It has an empirical formula that is C17H18FN3O3. The molecular weight of Ciprofloxacin 500mg is 331.4 g/mol.

What are The Drug Interactions with Ciprofloxacin 500 mg Hydrochloride Tablet?

Like other medications, there are drugs that you take at the same time with Ciprofloxacin 500 mg that interact with each other to make it less effective. Here is the presentation of a list of medications you need to take at least two or six hours before taking Ciprofloxacin 500mg . They are as follows:

1. Mineral supplements containing iron, magnesium, zinc etc. and vitamins
2. Ulcer medications such as antacids or sucralfate containing aluminium, magnesium etc
3. Videx powder or chewable tablets

You need to inform your doctor if you are on the following medicines:

1. Oral diabetes medicine
2. Antidepressants for depression or mental illness
3. Steroid drugs
4. Heart medicine, water pill, or diuretic
5. Blood thinner medicines such as Coumadin, Warfarin
6. Caffeine products
7. Non-Steroidal Anti-Inflammatory Drugs or NSAIDs that include naproxen, ibuprofen, celecoxib, meloxicam etc

You must note that there are other alternative medicines, such as herbal products, that can also interact with Ciprofloxacin 500 mg, which you need to be aware of.

Clinical Applications of Ciprofloxacin 500 mg:

This drug, called Ciprofloxacin 500 mg, is used to treat several bacterial infections. People who have had previous exposure to anthrax and plague can also use this medication for treatment. It would help if you remembered that it is possible that Fluroquinoline antibiotics exhibit several adverse effects that may not be reversible. Ciprofloxacin 500mg is the medicine you must use only for an infection you cannot treat with a safer antibiotic. The approval of the extended-release form of Ciprofloxacin 500mg is only given for use in adults.

What are The Dosage Guidelines for Ciprofloxacin 500 mg Tablets?

You should take Ciprofloxacin 500 mg as your doctor instructs you to take it.

You must read all the directions on the label and follow them. It is essential that you take Ciprofloxacin 500mg with or without food at the same time of the day.

To consume this drug in oral suspension or liquid form, you need to shake it well before you measure and take it. While taking your dosage, you need to use a dosing syringe or medicine dose-measuring device. It would help if you avoided all costs of taking Ciprofloxacin 500mg using a feeding tube.

You need to drink huge quantities of water while consuming this medication. You must never share this medicine with any other individual.

Missed Dosage Guidelines of Ciprofloxacin 500 mg:

If you miss a Ciprofloxacin 500 mg, the ideal solution is to consume it as soon as possible. You must not combine two doses and take them as one. Therefore, you need to skip the dose you miss if the time to take the next dose arrives.

Overdossage Guidelines of Ciprofloxacin 500 mg:

Firstly, as soon as you experience certain overdose symptoms, such as vomiting, nausea, black-coloured stools, blood in cough, or stomach pain, you need to seek medical assistance immediately to avoid severe complications. You can do this by calling your physician or a helpline number.

What are The Side Effects of Ciprofloxacin 500 mg Hydrochloride Tablets ?

Certain signs of allergic reactions may appear when you take Ciprofloxacin 500 mg, which you need to take note of. They are as follows:

1. Finding difficulty in breathing
2. Hives
3. Sore throat
4. Fever
5. Blistering and peeling
6. Burning eyes
7. Skin pain
8. Purple or red skin rash
9. Moodiness or changes in behaviour
10. Problem in tendons
11. Decrease in blood sugar level
12. Nerve damage
13. Nausea
14. Vomiting and diarrhoea
15. Abnormal liver function tests

If you notice the following medical conditions, you must inform your doctor immediately. They are as follows:

Rupturing of the tendon:

There is sudden pain, bruising, swelling, movement problems or a popping sound in any of your joints.

1. Symptoms of serious nerve damage:

They will include burning sensation in the hands, arms, legs, or feet, numbness, tingling etc.

• Low Blood sugar:

Signs will include irritability, dizziness, headache, hunger, rapid heart rate, and feeling of nausea.

• Change in moods:

Some symptoms include nervousness, hallucinations, paranoia, memory problems, agitation, confusion, and concentrating issues.

You need to note that in very rare circumstances, Ciprofloxacin 500 mg can cause damage to the aorta of your heart, which serves as the main blood artery of the body. It, in turn, can lead to a very dangerous type of bleeding or death.

Adverse Effects:

You may also experience serious adverse effects from taking Ciprofloxacin 500 mg. They are as follows:

1. Mild or severe skin rash
2. Jaundice is a condition in which there is yellowing of skin or eyes
3. Weakness of muscle
4. Having difficulty in breathing
5. No or very little urination
6. Rapid heartbeats
7. Dizziness
8. Increase in pressure inside the skull
9. Severe stomach pain
10. Watery or bloody diarrhoea

Things You Need to Avoid before Taking Ciprofloxacin 500 mg Tablet:

Firstly, if you are on Ciprofloxacin 500 mg, you need to avoid taking dairy products such as yoghurt or milk. Secondly, you must remember that while you can eat or drink these items, you must not use them while taking this medicine.

You must understand that antibiotic medication can trigger diarrhoea, which is a definite sign of the arrival of a new infection. Thus, if you have a watery or bloody stool, you need to call on your physician’s id before using an antidiarrhea medication.

The use of Ciprofloxacin 500 mg in medications can create a lot of sunburns. Therefore, it is essential that you adorn protective clothing and, along with it, use sunscreen.

Finally, if you are taking Ciprofloxacin 500mg, you must completely avoid doing any task, such as driving. This precaution you must take until you understand how this drug impacts your body.

Precautions:

Ciprofloxacin 500 mg is a medication that can trigger side effects that is inclusive of mood change, decreased damage to nerves, problems with tendons, and low blood pressure levels; therefore, if you are suffering from symptoms such as irritability, numbness, burning pain, confusion, agitation, paranoia, problems related to memory or concentration, suicidal thoughts, or even sudden pain or experiencing movement problems in your joints.

If, under rare circumstances, you experience damage to the aorta of your heart, which could trigger severe bleeding or even eventual death, then you need to seek medical assistance by contacting your doctor immediately.

If you feel frequent pain in your back, stomach, or chest, then you need to see your physician or healthcare professional immediately.

You must note that using this medication is impossible if you are suffering from a muscle disorder. You also need to inform your doctor if you have a past medical history of myasthenia gravis.

Before Taking Ciprofloxacin 500 mg Tablet, What Needs to be Done?

To begin with, if you are allergic to Ciprofloxacin 500 mg, then you need to stop consuming it. You must not take with this medication the following drugs. They are as follows:

1. Other fluoroquinolones such as norfloxacin, ofloxacin, levofloxacin, moxifloxacin etc.
2. Or also, if you are taking tizanidine

It would help if you remembered that consuming Ciprofloxacin 500mg could trigger tendon swelling or even tearing. It is especially seen in the Achilles tendon of the heel. This condition can occur either while you are undergoing treatment or several months after you stop taking Ciprofloxacin 500mg. To consume this medication with complete safety, you need to share with your doctor if you have had the following:

1. Problems with nerves
2. Myasthenia Gravis or muscle weakness
3. Heart attack
4. Kidney or liver disease
5. A seizure
6. Aneurysm or blood circulation problems
7. Diabetes
8. Long QT syndrome
9. Low potassium levels in the blood, also known as hypokalemia

What are The Storage Instructions for Ciprofloxacin 500 mg Tablets?

It is essential to store Ciprofloxacin 500 mg away from moisture and heat under room temperature. You must keep this medication from freezing and ensure you throw away unused liquid after 14 days.

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Brands of Ciprofloxacin 500 mg:

Some of the popular brands of Ciprofloxacin 500 mg include Cipro and Proquin XR.

Frequently Asked Questions:

Q. What types of bacteria does Ciprofloxacin 500 mg treat?

Ciprofloxacin 500 mg is a drug that functions by inhibiting DNA topoisomerase and DNA-gyrase. Therefore, this fluoroquinolone drug class is very effective in treating gram-negative bacilli. It is notably very efficient in dealing with Enterobacteriaceae like Salmonella spp, Shigella spp, and Escherichia coli.

Q. How long does Ciprofloxacin 500 mg take to exert its effect on the body?

This drug begins to function within a few hours of consuming it. However, you may only notice an improvement in treating bacterial infection symptoms after two or three days. In a few infections, such as osteomyelitis, using Ciprofloxacin 500 mg can take as much as a week to show improvement.

Q. Is Ciprofloxacin 500mg effective in treating Urinary Tract infections?

Patients with complex urinary tract infections can be treated with ciprofloxacin (UTI). According to a clinical research study, you can take this drug once-daily 500 mg to the typical twice-daily 500mg regimen orally over 7–20 days.

Q. Can Ciprofloxacin 500 mg increase urination?

The antibiotic Ciprofloxacin 500 mg may enhance the effects of glyburide’s blood sugar-lowering properties. You need to check for signs of low blood sugar, such as trembling, shaking, a rapid heartbeat, hunger, impaired vision, lightheadedness, or tingling in the hands or feet.

Q. Does Ciprofloxacin 500 mg help treat Urinary Tract infections in three days?

The lowest effective dose of Ciprofloxacin 500 mg to treat an uncomplicated urinary tract infection in women was 100 mg BID for 3 days. Statistics also show that Ciprofloxacin 500 mg therapy is slightly less effective than conventional Urinary Tract Infection treatment.

Q. When is the best time to take Ciprofloxacin 500 mg?

The blood or urine must be consistent for this medication to be effective. Therefore, you must avoid skipping any doses to maintain the amount. It is preferable to take the doses at regular intervals throughout the day and night if you are only supposed to take one dose per day;