What is Ciplox 500 mg?
Ciplox 500 mg is a ‘Fluoroquinolone’ antibiotic used in the treatment of several bacterial infections associated with urinary tract, nose, throat, skin, bones, joints, respiratory diseases, soft tissues and pneumonia (infection in lungs). Ciplox 500 mg is an oral medication, intravenous route, and eye and ear drops. Ciplox 500 mg is also taken in combination with another antibiotic medicine.
This medicine works against a mix of some Gram-Positive and many Gram-Negative bacteria. It works by inhibiting I topoisomerase (DNA gyrase) along with topoisomerase IV. These are enzymes that are needed to separate bacterial DNA and therefore stimulate the inhibition of cell division. But, the process of bacterial DNA Fragmentation gets triggered due to the inhibition of these enzymes.
Ciplox 500 mg received its patent in 1980 and was released for public consumption in 1987.
This drug is a part of the World Health Organization’s list of essential medicines. In the year 2019, Ciplox 500 mg was the 113th most prescribed medication in the United States of America, recording about five million prescriptions sales.
How does Ciplox 500 mg Tablet Work?
Ciplox 500 mg is a medicine that inhibits the enzymes I topoisomerase (DNA gyrase) and topoisomerase IV. These enzymes function to divide the bacterial DNA to trigger the inhibition of cell division. Therefore, it is the bacterial DNA Fragmentation procedure that is initiated by the inhibition of these enzymes.
The chemical structure of Ciplox 500mg is 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid. The empirical formula of this medicine is C17H18FN3O3, and the molecular weight is 394.3.
What are The Drugs That Interact with Ciplox 500 mg?
In terms of drug interactions, a few drugs, when taken along with Ciplox 500 mg, can harm its effects. Therefore, if you take any medications mentioned below, you must take Ciplox 500mg two hours before or six hours after.
- Videx (Didanosine) powder
- Vitamins or mineral supplements containing iron, zinc, or magnesium
- Ulcer medications such as antacids or sucralfate
You need to call and inform your doctor if you are on drugs such as:
- Diabetic medication
- Blood thinner medicines such as Warfarin, Coumadin etc
- Steroidal medicines such as Prednisone
- Caffeine products
- NSAID drugs such as aspirin, ibuprofen
- Heart medicine or a diuretic/ water pill
Above all, you need to note that there, in total, six hundred and twenty-five drugs interact with Ciplox 500mg. This medicine also possesses ten disease interactions and three alcohol food interactions. Out of the total drug interactions, 151 are in the majority, 390 are moderate, and 84 are minor.
Some of the brand names of Ciplox 500mg include Proquin XR and Cipro.
Clinical Application of Ciplox 500 mg:
Fluoroquinolone antibiotic Ciplox 500 mg is used to treat several bacterial illnesses. People exposed to anthrax or specific types of plague are also treated with it. You can use Ciplox 500mg extended-release only for adults.
Fluoroquinolone drugs have potentially irreversible, significant, or debilitating adverse effects.
Only infections you cannot cure with a less dangerous antibiotic should you treat with ciprofloxacin.
What are The Dosage Guidelines of Ciplox 500 mg Tablets?
You should follow your doctor’s instructions with precision as directed while taking Ciplox 500 mg. It is essential that you look up drug guides or instruction sheets and adhere to all instructions on your prescription label.
This drug you must take every day at the same time, with or without food.
Before measuring a dose, you must shake the oral suspension (liquid) for 15 seconds. It would help if you used pharmaceutical dose-measuring equipment or the dosing syringe while measuring the dose. Consuming Ciplox 500mg oral suspension through a feeding tube is not recommended.
Use Ciplox 500mg for the recommended dosage, even if your symptoms disappear rapidly, since missing doses can increase your risk of developing a drug-resistant infection. It is essential to note that a viral infection is like the flu or a cold that you cannot treat with this medicine.
What Needs to be Done When You Miss A Dose of Ciplox 500 mg?
- Take Ciplox 500 mg as soon as possible if you take regular pills or oral suspension. You must avoid missed dosage if your next dose is fast approaching in less than 6 hours.
- When you consume extended-release tablets of Ciplox 500mg, you should take the medication as soon as you remember, but avoid taking the missed dose if it will be less than 8 hours before your next dose.
- Never combine two dosages of this medicine into one.
What Needs to be Done If You are Overdosing on Ciplox 500 mg ?
If you overdose on Ciplox 500mg, you need to look for medical assistance immediately by calling your doctor or contacting a helpline number.
What are The Side Effects of Ciplox 500 mg Tablets?
Ciplox 500 mg can trigger severe side effects, such as tendon issues, potentially irreversible nerve damage, severe mood or behavioural changes after just one dose, or low blood sugar level leading to a comma.
Suppose you experience symptoms of an allergic reaction to ciprofloxacin (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction. In that case, you need to find medical assistance. A few symptoms include fever, sore throat, burning in your eyes, skin pain, and red or purple skin rash that spreads and causes blistering and peeling.
You need to call on your physician immediately if you have the following adverse medical conditions from consuming Ciplox 500mg:
- Tendon rupture: Sudden swelling, bruising, tenderness, snapping or popping sound in your joints.
- Mood alteration: Confusion, nervousness, paranoia, memory problems, hallucinations, concentration problems, suicidal thoughts etc.
- Damaged nerves: Tingling, burning pain in hands, arms, legs, numbness
- Decrease blood sugar level: Hunger, nausea, dizziness, headache, hunger, fast heart rate, shaky feeling etc.
Ensure that you call your doctor and stop using Ciplox 500mg if you have the following symptoms:
- Jaundice (eyes or skin that turns yellow)
- Low quantity urine
- Any skin rash
- Symptoms of elevated skull pressure include severe headaches, ringing in the ears, nausea, dizziness, and pain behind the eyes.
- Rapid or hammering heartbeats, chest fluttering, shortness of breath, and an unexpected feeling of vertigo
- Respiratory issues and weakening of the muscles
- Severe abdominal pain
Precautions You Need to Take before Consuming Ciplox 500 mg Tablets
Ciplox 500 mg you must avoid taking with dairy products like milk or yoghurt or with juice that has calcium added. While taking this medication, you may eat or drink these items with meals but avoid taking them individually.
Diarrhoea brought on by Ciplox 500mg may signal the onset of a new infection. Before taking anti-diarrhoea medication, call your doctor, especially if your diarrhoea is watery or bloody.
You could burn more readily if you use Ciplox 500mg. Steer clear of the sun and tanning beds. When you are outside, you need to get into a protective gear and use sunscreen (SPF 30 or greater). If you experience intense burning, redness, itching, rash, or swelling after sun exposure, let your doctor know immediately.
Until you know how Ciplox 500mg will affect you, avoid driving or engaging in other risky activities, especially since your reflexes may become slower if you consume this drug.
Rarely, the antibiotic Ciplox 500mg may harm your aorta, resulting in life-threatening bleeding or even death. Get emergency medical attention if you experience severe, persistent back, stomach, or chest pain.
If you suffer from a muscle issue, you might be unable to use this medication. If you have a history of myasthenia gravis, let your doctor know.
Frequently Asked Questions
Q. Is the antibiotic Ciplox 500 mg effective?
The antibiotic ciprofloxacin or Ciplox 500 mg effectively against various positive and negative bacteria and illnesses. There are other antibiotics like this medication also available that you can use to treat more diverse or severe infections. However, “stronger” antibiotics are not always the best option.
Q. How long does the body retain Ciplox 500mg?
Around 22 hours after your final dose of Ciplox 500 mg, it should be completely gone from your body. With normal renal function, the half-life of this drug in the serum is 4 hours.
Q. What risks do you associate with taking Ciplox 500 mg?
Cipro may make people of all ages more susceptible to tendinitis, tendon rupture, and peripheral neuropathy. Secondly, they can also have serious side effects, including nerve pain and a pins-and-needles sensation, tingling, or weakening of the muscles and joints.
Q. What meals are safe for me to eat while taking Ciplox 500 mg?
When taking Ciplox 500 mg, you can have dairy products and meals with added calcium as part of a regular meal. But They might reduce the medication’s effectiveness. This drug may not function when taken along with enteral (tube) feedings.
Q. Can Ciplox 500 mg lead to cardiac issues?
Ciplox 500 mg is an antibiotic that raises the possibility of major heart issues like aortic aneurysms, heart valve damage, heart failure, and heart attacks.
Q. Is Ciplox 500 mg a sleep-inducing drug?
Some people may experience lightheadedness, drowsiness, or decreased alertness while taking Ciplox 500 mg. Until you are certain of how this medication affects you, avoid driving or engaging in any activity that could be hazardous. Therefore, you must consult your doctor if these reactions are extremely bothersome.