Aromasin 20mg Tablets

What is Aromasin 20mg?

Aromasin 20mg is a medication that consists of Exemestane which is used in the treatment of certain breast cancer. Typically, the drug is developed for postmenopausal women. It also belongs to a family of drugs known as ‘Antiestrogens or Aromatase Inhibitors. Aromasin 20mg essentially proves to be effective in treating ‘Breast Cancer’ that develops rapidly due to estrogen stimulation in a woman.

Aromasin (Exemestane) 20mg is an antiestrogen (Aromatase Inhibitor) used for adjuvant treatment of postmenopausal women with hormone-receptor positive early breast cancer who are with two to three years of tamoxifen which is switched to completion of five consecutive years of adjuvant hormonal therapy. This medication you can also use to prevent ‘Breast Cancer relapse from occurring. Aromasin 20mg essentially inhibits ‘Aromatase,’ an enzyme that synthesizes estrogen in a female—eventually resulting in the lowering of the ‘Sex Hormone’ level to reduce the rate of Breast Cancer growth.

Aromasin 20mg was for the first time developed as an ‘Irreversible Aromatase Inhibitor’ in the year 1987. However, after about twelve years, in October 1999, this medication finally received its official approval for clinical use by the United States of America FDA (Food and Drug Administration). This drug is also helpful in treating women whose Breast Cancer symptoms worsened after they took the medicine tamoxifen.

How does Aromasin 20mg Act to Manage Recurrent ‘Breast Cancer Symptoms?

Firstly, you must understand that one of the significant causes of Breast Cancer in females is the sex hormone estrogen. Secondly, you must also note that ‘Aromatase’ is an enzyme in the body that helps in converting androgens to estrogens in pre-and postmenopausal women. Now, the estrogen circulating in a postmenopausal woman is available simply due to the conversion of adrenal and ovarian androgens (testosterone and androstenedione) to estrogens (estradiol and estrone) that occurs triggered by the aromatase enzyme. Therefore, blocking the enzyme Aromasin 20mg and reducing its level prevents Breast Cancer from reappearing again.

Medical Usage of Aromasin 20mg Tablet;

Aromasin 20mg is used in the form of a ‘Hormone Therapy’ for managing the symptoms of Breast Cancer. Aromasin 20mg is an effective aromatase inhibitor medication used in the treatment of ‘Hormone Receptor Positive type cancer of the breast. There are some breast cancers that grow at a rapid rate due to the hormone estrogen. Aromasin 20 mg is an antiestrogen that helps to reduce the synthesis of estrogen to enhance the treatment of breast cancer. It works to prevent the synthesis of estrogen that helps in minimising the estrogen level to reduce the growth of cancers.

Aromasin 20mg is indicated for use in adjuvant treatment in post-menopausal women suffering from estrogen receptor positive early breast cancer. Also, you can use this medication in the advanced breast cancer treatment in postmenopausal women. This is especially done because this medical condition has got worse following tamoxifen therapy.

How to Take Aromasin 20mg Tablet?

Before taking a dose of Aromasin 20mg, you need to know how to take this medication if you want to avoid experiencing undesirable side effects, some of which may prove fatal. Hence here is presenting to you a few insights usually given by your healthcare professional explaining how to consume Aromasin 20mg. 

1. Inform your doctor if you have issues with drug allergies 
2. Due to the risk of acquiring mild to severe side effects, you must avoid taking this drug if you are pregnant or breastfeeding. 
3. Herbal products such as St John’s wort are incompatible with this medication and may cause adverse drug interactions when taken together. Hence, avoiding using organic medicine along with this drug is advisable.
4. Suppose you have previously had or currently suffer from a medical condition like osteoporosis, renal or liver damage, etc. It will help if you inform your doctor before using this drug to avoid adverse side effects that may prove to be lethal.

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When to Take Aromasin 20mg Tablet?

      Like any other synthetic drug, when you take Aromasin 20mg at the right time and the right way, you improve your chances of deriving maximum benefits; it is, therefore, necessary that you learn to take Aromasin 20 mg appropriately. Here is presenting to you a few tips: 

1. Firstly, you must remember to take Aromasin 20 mg orally via the mouth. Usually once a day after meals, preferably. 
2. To acquire maximum benefits from taking this drug to treat recurrent breast cancer symptoms, you should take it at the same time daily. 
3. To use this medication correctly and avoid adverse effects, you must follow all prescription label instructions and directions the pharmacist provides. 
4. For this medication to be effective, you must keep taking it continuously for many years. 
5. Keep taking this medicine even if you are not keeping well.

What are The Dosage Guidelines of Aromasin 20mg Tablets?

The dosage plan of Aromasin 20mg for treating symptoms of recurring Breast Cancer is as follows: 

Usual Aromasin 20mg Dosage for Breast Cancer:

The minimum initial dose of Aromasin 20mg is 25 mg to be taken orally at least once daily. Also, while consuming this medicine, you must remember that premenopausal women cannot use it.

Even in case you are suffering from renal or hepatic dysfunction, there is no need for you to adjust the dosage. However, suppose you are consuming an Aromasin 20 mg dosage and a powerful CYP450 3A4 inducer drug like rifampin. After a meal, you need to adjust the minimum dose to 50 mg daily.

If you have advanced breast cancer, the minimum dosage is 25 mg once a day after a meal. As for Paediatric dosage, the United States of America FDA has not approved this medication for clinical usage in breast cancer children because this medication has not yet undergone testing for safety and efficacy.

You must note that your doctor shall prescribe a dose of Aromasin 20 mg, keeping in mind a few factors. These will include the following:

.1.  Age

Type and severity of the breast cancer
The mode of administration of the drug

4,  Finally, all the other medical conditions you may have had in the past

Usually, your physician will prescribe a minimum dosage to start the medicinal therapy. The dosing will then gradually, under the supervision of your healthcare professional, undergo adjustment over some time. It is until you find the correct dose for your body. Also, you must remember that ultimately your doctor will select a practical minimum and not maximum dosage that gives you the desired effect. You must understand that you do not self-prescribe but take only the dose that your physician prescribes.

While following this simple schedule, you may either miss a dose or overdose on it. for this, follow the guidelines as below;

Missed Dosage:

If you are skipping a dose of Aromasin 20mg, you must take it as soon as you remember. However, if the time to take your following amount is just around the corner, you must refrain from taking the skipped dose. 

Overdosing:

If by chance you overdose on Aromasin 20mg, there is a chance that you may experience severe side effects, which, when not treated, can be fatal. Hence, you need to call your doctor immediately in such a situation.

What are The Side Effects of Aromasin 20mg Tablets?

When you take a synthetic drug like Aromasin 20mg, there is always the danger of experiencing a few mild and severe side effects. They are: 

Side-effects:

1. Increase in appetite 
2. Fatigue or feeling of tiredness 
3. Excessive sweating 
4. Hot flashes 
5. Nausea 

Adverse effects:

If you observe any of the severe side effects below, you need to stop taking Aromasin 20mg and start talking to your doctor.

1. Bone loss which is the most severe side-effect
2. Lack of sleep or Insomnia
3. Pain in the joints
4. Headaches
5. Reduces fertility rate

Alternative Medications That You can Use in Place of Aromasin 20mg:

  If you cannot take Aromasin 20mg for any medical reason such as ‘Allergy,’ then you can take in place of it a few other medicines that contain ‘Exemestane .’They include: 

1. FCE-24304

Frequently Asked Questions:

Q. How rapidly does Aromasin 20mg lower estrogen?

Taking a single dose of Aromasin 20mg takes about a minimum of two to three days and a maximum of four to five days to lower estrogen levels in the female body. 

Q. When do you stop taking Aromasin 20mg?

Usually, most women suffering from recurrent ‘Breast Cancer’ take Aromasin 20mg for at least two to three years. There is a possibility of doctors prescribing it for a much longer time.   

Q. What precautions do you need to consider while taking Aromasin 20mg?

There are a couple of safety measures that you need to keep in mind while using Aromasin 20mg. They are as follows: 

1. Do not take it if you are premenopausal women 
2. Avoid consuming Aromasin 20mg if you are suffering osteoporosis or renal or hepatic damage 

Q. How do you store Aromasin 20mg effectively to preserve its efficacy?

If you want to use Aromasin 20mg effectively, you must store it well. Here is presenting a few storage guidelines that you need to follow: 

1. Keep it as far as possible from pets and children. 
2. Store this medication in an airtight container away from light and heat under room temperature 
3. Do not discard this medication by flushing it down the toilet drain. Permanently remove drug dosage following instructions given by the pharmacist or waste disposal company. 

Q. Is there a difference between Aromasin 20mg and tamoxifen?

No, there is no difference between Aromasin 20 mg and tamoxifen. Both these drugs have received approval for clinical use by the United States of America Food and Drug Administration or FDA for breast cancer treatment. You can use tamoxifen to treat ductal carcinoma in situ. 

Q. Can males use Aromasin 20 mg?

Yes, a man diagnosed with breast cancer can use Aromasin 20 mg. Usually, a male will need to take this medication for about five to ten years. However, if a drug like tamoxifen does not prove to be suitable for you, your doctor will recommend Aromasin 20 mg, an aromatase inhibitor. 

Q. Is it possible that consuming Aromasin 20 mg can lead to sexual dysfunction?

Typically, the regular use of Aromasin 20 mg does not cause sexual dysfunction. This medication, however, can have an impact on estrogen and women. It can trigger vaginal dryness and hot flashes that can stop a female from enjoying a healthy sex life. If you are a woman looking to use Aromasin 20 mg for breast cancer, you need to consult your doctor and speak about it in detail.