Naloxone is a medication used to treat opioid overdose. It is an opioid antagonist, which means it binds to opioid receptors in the brain and blocks the effects of opioids, such as pain relief, sedation, and respiratory depression. Naloxone can quickly reverse the potentially life-threatening effects of opioids and restore normal breathing in people who have overdosed. It is often administered by injection or nasal spray by healthcare professionals or emergency responders. In some countries, naloxone is available without a prescription and can be obtained by individuals who are at risk of opioid overdose or their family members or friends. Naloxone is an essential tool in combating the opioid epidemic and saving lives from overdose.