Hypogonadism is a medical condition in which the body does not produce enough testosterone, which is the primary male sex hormone responsible for the development of male reproductive tissues and secondary sexual characteristics. Hypogonadism can occur due to a variety of factors, including genetic disorders, injury or infection to the testicles, chemotherapy or radiation therapy for cancer, or certain medications.

There are two main types of hypogonadism: primary and secondary. Primary hypogonadism occurs when there is a problem with the testicles themselves, such as a genetic disorder or injury. Secondary hypogonadism occurs when there is a problem with the pituitary gland or hypothalamus in the brain, which regulate testosterone production.

Symptoms of hypogonadism in males may include decreased libido, erectile dysfunction, decreased muscle mass, decreased bone density, and fatigue. In children, hypogonadism can cause delayed puberty or incomplete development of sexual characteristics.

Hypogonadism can be diagnosed through blood tests to measure testosterone levels, luteinizing hormone (LH), and follicle-stimulating hormone (FSH). Treatment for hypogonadism may involve testosterone replacement therapy (TRT) to increase testosterone levels in the body. TRT can be administered through injections, gels, patches, and pellets implanted under the skin. The dosage and duration of treatment will depend on the individual’s age, overall health, and the severity of their hypogonadism. It is important for individuals with hypogonadism to discuss their treatment options with a healthcare provider.

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