Dihydrotestosterone (DHT) is a hormone that is formed from testosterone through the action of the enzyme 5-alpha-reductase. DHT is a more potent androgen than testosterone and plays an important role in the development and maintenance of male sex characteristics.
DHT is primarily produced in the prostate gland, hair follicles, and testes, but it is also present in other tissues throughout the body. In the prostate gland, DHT is responsible for stimulating the growth and differentiation of the glandular tissue, and it is also involved in the development of male pattern baldness.
In addition to its role in male sexual development, DHT is also involved in the development and maintenance of muscle mass and bone density. However, elevated levels of DHT have been associated with an increased risk of prostate cancer, benign prostatic hyperplasia (BPH), and other health problems.
Because of its role in male pattern baldness and prostate health, DHT has been the target of pharmaceutical interventions, including 5-alpha-reductase inhibitors, which are used to reduce the conversion of testosterone to DHT in the body. However, the long-term effects of these drugs on overall health are still being studied, and they can also have negative side effects, including decreased libido, erectile dysfunction, and breast enlargement.