Cholestatic hepatitis is a type of liver disease characterized by impaired bile flow, which can lead to inflammation and damage to the liver cells. Bile is a fluid produced by the liver and stored in the gallbladder that helps in digestion and the elimination of waste products from the body.
Cholestatic hepatitis can be caused by a number of factors, including infections, medications, toxins, autoimmune disorders, and inherited genetic conditions. Some common causes of cholestatic hepatitis include viral hepatitis, such as hepatitis A, B, and C, autoimmune hepatitis, primary biliary cholangitis, and drug-induced liver injury.
Symptoms of cholestatic hepatitis may include fatigue, jaundice, itching, abdominal pain, nausea, and vomiting. In severe cases, it can lead to complications such as cirrhosis, liver failure, and an increased risk of liver cancer.
The diagnosis of cholestatic hepatitis is made through blood tests that evaluate liver function, as well as imaging studies such as an ultrasound, CT scan, or MRI. A liver biopsy may also be performed to confirm the diagnosis and assess the extent of liver damage.
Treatment for cholestatic hepatitis depends on the underlying cause and may include medications to improve bile flow and reduce inflammation, as well as lifestyle changes such as avoiding alcohol and following a healthy diet. In some cases, a liver transplant may be necessary if the liver is severely damaged.
It is important to seek medical attention if you have symptoms of cholestatic hepatitis or if you have a history of liver disease, as early diagnosis and treatment can help to prevent complications and improve outcomes.